Cannot start Ares patched YR

[eva-251]

Yes. Defense+ was the first thing I went to when I checked to see if it was the culprit (as I knew the auto-sandboxing prevented GIMP plug-ins from functioning, figured this could be an issue too).
Made sure everything involved (ra2md, gamemd, ares.dll, syringe.exe, ares.dll.inj) was trusted and not sandbox'd. When that didn't work, I disabled Defense+; when that didn't work, I disabled everything.

Considering the addition of Comodo has been the most significant software change to my PC since I last ran YR w/Ares, I will try uninstalling it some time later tonight or tomorrow, to see if that remedies the problem.